Grupos de Investigación
Sede San Martín

Laboratorio de Procesos Fermentativos

Integrantes

Director:
Dr. Miguel Ángel Galvagno

Investigador Principal del CONICET
IIB-INTECH Sede San Martín
Profesor UNSAM y UBA
Miembros:
Dr. Diego Gabriel Noseda
Investigador Adjunto del CONICET
IIB-INTECH Sede San Martín
Jefe Trabajos Prácticos UNSAM
email: diegonoseda@yahoo.com.ar

Dra. Valeria Castilla

Lic. Guido Novellio

Líneas de investigación

Produccion de biocombustibles por conversion de residuos agro industriales y municipales utilizando ingenieria metabolica inversa , con enfasis en streses y ecanismos de tolerancia en levaduras industriales.

Producción de metabolitos en levaduras transformadas geneticamente mediante procesos fermentativos en bioreactor de tanque agitado

Publicaciones recientes

  1. Guido F. Novelli Poisson, Angela B. Juarez, Diego G. Noseda, María C. Ríos de Molina, Miguel A. Galvagno. Adaptive Evolution Strategy to Enhance the Performance of Scheffersomyces stipitis for Industrial Cellulosic Ethanol Production. Industrial Biotechnology 16(5) 281-289: 2020.
  2. Structural and functional comparison of SARS‑CoV‑2‑spike receptor binding domain produced in Pichia pastoris and mammalian cells. Scientific Reports 2020. Argentinian AntiCovid Consortium (D. G. Noseda as co-autor).
  3. Improved fermentation strategies in a bioreactor for enhancing poly(3-hydroxybutyrate) (PHB) production by wild type Cupriavidus necator from fructose. Daiana Nygaard, Oxana Yashchuk, Diego G. Noseda, Beatriz Araoz, Elida B. Hermida. Heliyon 2021
  4. Limeres, M. J., Gomez, E. R., Noseda, D. G., Cerrudo, C. S., Ghiringhelli, P. D., Nusblat, A. D. and Cuestas, M. L. Impact of hepatitis B virus genotype F on in vitro diagnosis: detection efficiency of HBsAg from Amerindian subgenotypes F1b and F4. Archives of Virology(2019).
  5. Gurdo, N., Calafat, M., Noseda, D.G. and Gigli, I. Production of Selenium-Enriched Yeast (Kluyveromyces marxianus) Biomass in a whey-based Culture Medium. American Journal of Biochemistry and Biotechnology 14 (2): 175-182 (2018)
  6. Gastón Ortiz, Diego Noseda, Clara Ponce Mora, Matías Recupero, Martín Blasco, and Edgardo Albertó. A Comparative Study of New Aspergillus Strains for Proteolytic Enzymes Production by Solid State Fermentation. Enzyme Research, Volume 2016, Article ID 3016149, 11 pages.
  7. Diego Noseda, Matías Recúpero, Martín Blasco, Joaquín Bozzo, Miguel Galvagno Production in stirred-tank bioreactor of recombinant bovine chymosin B by a high-level expression transformant clone of Pichia pastoris. Protein Expression and Purification 123 (2016) 112-121.
  8. Nicolás Mongiardino Koch, Ignacio Soto, Esteban. Hasson, Miguel Galvagno and Leopoldo Iannone. Biodiversity of cactophilic microorganisms in western Argentina: community structure and species composition in the necroses of two sympatric cactus hosts. Fungal Ecology (2015) 13: 167-180.
  9. Diego Noseda, Martín Blasco, Matías Recúpero and Miguel Galvagno. Bioprocess and downstream optimization of recombinant bovine chymosin B in Pichia pastoris under methanol-inducible AOXI promoter. Protein Expression and Purification (2014) 104: 85–91.
  10. Diego Kingston, Guido Novelli, Patricia Cerrutti, Matias Recupero, Martin Blasco and Miguel Galvagno. Use of grape pomaces to produce biomass of Pichia (Komagataella) pastoris strain expressing a bovine chymosin activity. Food Science and Nutrition (2014) 2: 734-43.
  11. Diego Noseda, Matías Recúpero, Martín Blasco, Gaston Ortiz and Miguel Galvagno. Cloning, expression and optimized production in a bioreactor of bovine chymosin B in Pichia pastoris under AOXI promoter. Protein Expression and Purification (2013) 92: 235–244.
  12. Analía Vazquez, Laura Foresti, Patricia Cerrutti and Miguel Galvagno. Bacterial cellulose from simple and low cost production media by Gluconacetobacter xylinus. Journal of Polymers and the Environment (2013) 21(2): 545-554.
  13. Romina Armando, Miguel Galvagno, Cecilia Dogi, Patricia Cerrutti, Ana Dalcero, Lilia Cavaglieri. Statistical optimization of culture conditions for biomass production of probiotic gut-borne Saccharomyces cerevisiae strain able to bind fumonisin B1. Journal of Applied Microbiology (2013) 114(5):1338-1346.
  14. Patricio Santagapita, Silvina Rosa, Florencia Mazzobre, Mario Cueto, Pilar Buera and Miguel Galvagno. Differential scanning calorimetry evaluation of oxidation stability of docosahexaenoic acid in microalgae cells and their extracts. International Journal of Food Science and Technology (2013) 48: 1729-1735.